133576-73-5Relevant academic research and scientific papers
EPC-synthesis of functionalised amides via chiral β-nitrogenated organolithium compounds
Foubelo, Francisco,Yus, Miguel
, p. 2911 - 2922 (2007/10/03)
The deprotonation of chiral chloroamides or carbamates 1, 4, 7, 10, 13 and 16 with n-butyllithium followed by in situ lithiation with lithium naphthalenide, both at -78°C in THF, leads to the formation of the corresponding chiral dianionic intermediates,
Synthesis of enantiomerically pure functionalised amides (EPC-synthesis) from chiral β-aminated organolithium intermediates
Foubelo, Francisco,Yus, Miguel
, p. 4831 - 4834 (2007/10/02)
The successive deprotonation-lithiation of chiral chloroamides 1 with n-butyllithium and lithium naphthalenide, respectively, at -78°C leads to the corresponding chiral β-aminated organolithium intermediates 2, which by reaction with different electrophil
