133576-76-8 Usage
Uses
Used in Pharmaceutical Research:
(1R,2S)-N-Piperidinonorephedrine is used as a research compound for studying the effects of noradrenaline reuptake inhibition on cognitive function, energy levels, and appetite regulation. Its psychoactive properties and the potential therapeutic benefits it may offer are of interest to scientists exploring new treatments for various conditions.
Used in Drug Development:
In the field of drug development, (1R,2S)-N-Piperidinonorephedrine serves as a lead compound for the creation of new medications that aim to harness its noradrenaline-increasing effects while minimizing the associated risks. This could potentially lead to the development of safer and more effective treatments for conditions that may benefit from increased norepinephrine levels.
Used in Regulatory and Safety Studies:
(1R,2S)-N-Piperidinonorephedrine is also used in regulatory and safety studies to understand the potential risks associated with its use, including the risk of addiction and dependence. These studies are crucial for establishing guidelines and regulations to ensure the safe use of (1R,2S)-N-Piperidinonorephedrine in any potential medical applications.
Check Digit Verification of cas no
The CAS Registry Mumber 133576-76-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,3,5,7 and 6 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 133576-76:
(8*1)+(7*3)+(6*3)+(5*5)+(4*7)+(3*6)+(2*7)+(1*6)=138
138 % 10 = 8
So 133576-76-8 is a valid CAS Registry Number.
133576-76-8Relevant academic research and scientific papers
Enantioselective Addition of Diethylzinc to α-Branched Aldehydes
Kang, Jahyo,Lee, Jun Won,Kim, Joo In
, p. 2009 - 2010 (2007/10/02)
Reaction of diethylzinc with α-branched aldehydes in the presence of a catalytic amount of (1R,2S)-(-)-1-phenyl-2-piperidinopropane-1-thiol 1 provided the corresponding secondary alcohols in almost 100percent enantiomeric excess.
Chiral Arene Chromium Tricarbonyl Complexes as Enantioselective Catalysts: Highly Selective 1,2-Alkyl Additions to Aldehydes
Heaton, Steven B.,Jones, Graham B.
, p. 1693 - 1696 (2007/10/02)
The preparation of a rationally designed catalyst system derived from norephedrine is reported.The key stereodirective element emanates from a chromium tricarbonyl group complexed to one face of the aryl ring.The catalysts mediate the addition of diethyl zinc to a variety of aldehydes with extremely high enantioselectivity.Key Words: enantioselective catalyst; norephedrine; arene chromium tricarbonyl; diethyl zinc; chiral 1,2-addition
