133587-48-1Relevant academic research and scientific papers
Dihydroindenoindole compounds and methods for using the same
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, (2008/06/13)
Compounds of the formula STR1 wherein R is hydrogen or a lower alkyl group, R1 and R2 are independently selected from hydrogen or a lower alkyl group, R3, R4 and R6 are independently selected from hydrogen, halogen or a lower alkyl group, R5 is hydrogen, hydroxy, halogen, a lower alkyl group, a lower alkoxy group, a mono- or di-lower alkylamino group, NH2 or NR11 COR12, R7, R8, R9 and R10 are independently selected from hydrogen, hydroxy, a lower alkyl group, a lower alkoxy group, a mono- or di-lower alkylamino group, NH2 or NR11 COR12, R11 is a hydrogen or a lower alkyl group, R12 is a lower alkyl group, with the proviso that when R is hydrogen then at least one of the substituents R1 to R10 is not hydrogen, or a salt thereof, are useful as antioxidants, within the medical and non-medical field, and that when R is hydrogen, methyl or neopentyl in formula IA, then at least one of R1 to R10 is not hydrogen. Many of the compounds of formula IA and IB are new and various methods for preparing them are described.
NEW ANTIOXIDANTS INCORPORATING INDOLE AND INDOLINE CHROMOPHORES
Brown, David W.,Graupner, Paul R.,Sainsbury, Malcolm,Shertzer, Howard G.
, p. 4383 - 4408 (2007/10/02)
Syntheses of potent antioxidants utilising indenoidole or indenoidoline pharmacophores are described.The antioxidant behaviour and the oxidation potentials of these compounds are correlated, and some of their reactions with radicals are noted.
