133603-96-0

Upstream product

• 3187-83-5 (R,R)-N,N'-bis(salicylidene)-1,2-cyclohexanediamine 
• 20439-47-8 (1R,2R)-1,2-diaminocyclohexane 
• 89-95-2 2-methyl-benzyl alcohol 
• 215057-24-2 2,2'-(1E,1'E)-(1R,2R)-cyclohexane-1,2-diylbis(azan-1-yl-1-ylidene)bis(methan-1-yl-1-ylidene)diphenol 

Downstream Products

• 870258-69-8 1-[(2S,3S,4aR,8aR)-4-Acetyl-2,3-bis-(2-hydroxy-phenyl)-octahydro-quinoxalin-1-yl]-ethanone 
• 870258-68-7 [(2S,3S,4aR,8aR)-4-Benzoyl-2,3-bis-(2-hydroxy-phenyl)-octahydro-quinoxalin-1-yl]-phenyl-methanone 
• 133604-01-0 C₃₄H₃₆N₂O₂ 
• 870258-70-1 [(2S,3S,4aR,8aR)-4-(3,5-Dimethyl-benzoyl)-2,3-bis-(2-hydroxy-phenyl)-octahydro-quinoxalin-1-yl]-(3,5-dimethyl-phenyl)-methanone 
• 934373-93-0 [(2S,3S,4aR,8aR)-2,3-Bis-(2-hydroxy-phenyl)-4-(4-methyl-benzoyl)-octahydro-quinoxalin-1-yl]-p-tolyl-methanone 

Relevant academic research and scientific papers

Practical by ligand design: A new class of monodentate phosphoramidite ligands for rhodium-catalyzed enantioselective hydrogenations

A new class of low-cost and easy-to-prepare monodentate phosphoramidite ligands (Cydam-Phos) has been developed from readily accessible and cheap trans-1,2-diaminocyclohexane as starting material through a three-step transformation. This type of ligands exhibited excellent enantioseletivities and high activities in rhodium(I)-catalyzed asymmetric hydrogenations of dehydro-α-amino acid methyl esters 9 (ee: 96.2-99.8%) and acetylenamides 11 (91.8-98.8%). The remarkable substituent effects exhibited by the ligands on the enantioselective control of the catalysis are rationalized on the basis of molecular structure of the catalyst precursor.

Synthesis of enantiomerically pure C2-symmetric acyclic and cyclic 1,2-diamines via pinacol coupling of imines

The inter- and intramolecular coupling of imines promoted by samarium diiodide and Lewis acids or by Zn/MsOH was extensively studied. The intramolecular reaction of chiral, enantiomerically pure bis-imines was also considered, and allowed the efficient, s

Electroorganic Chemistry. 129. Electroreductive Synthesis of Chiral Piperazines and Enantioselective Addition of Diethylzinc to Aldehydes in the Presence of the Chiral Piperazines

Electroreduction of diimines, prepared from 1,2-diamines and aromatic aldehydes, in acidic media gave intramolecularly coupled products, 2,3-diarylpiperazines, stereoselectively.Chiral tri- and tetrasubstituted piperazines were synthesized effectively fro