133605-26-2 Usage
Description
2-(BROMOMETHYL)-1-NITRO-3-(TRIFLUOROMETHYL)BENZENE is a chemical compound with the molecular formula C8H6BrF3NO2. It is an organic compound containing a benzene ring substituted with a bromomethyl group, a nitro group, and a trifluoromethyl group. 2-(BROMOMETHYL)-1-NITRO-3-(TRIFLUOROMETHYL)BENZENE is commonly used in organic synthesis and medicinal chemistry as a building block for the synthesis of more complex molecules. It has potential applications in the pharmaceutical and agrochemical industries. Due to its highly reactive nature, it should be handled with caution to avoid potential hazards.
Uses
Used in Organic Synthesis:
2-(BROMOMETHYL)-1-NITRO-3-(TRIFLUOROMETHYL)BENZENE is used as a building block in organic synthesis for the creation of more complex molecules. Its unique structure allows for various chemical reactions, making it a valuable component in the synthesis of advanced organic compounds.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 2-(BROMOMETHYL)-1-NITRO-3-(TRIFLUOROMETHYL)BENZENE serves as a key intermediate in the development of new pharmaceuticals. Its presence in the molecular structure can contribute to the desired pharmacological properties of the final drug product.
Used in Pharmaceutical Industry:
2-(BROMOMETHYL)-1-NITRO-3-(TRIFLUOROMETHYL)BENZENE is utilized in the pharmaceutical industry for the synthesis of drugs with potential therapeutic applications. Its unique functional groups can be manipulated to create molecules with specific biological activities.
Used in Agrochemical Industry:
2-(BROMOMETHYL)-1-NITRO-3-(TRIFLUOROMETHYL)BENZENE also finds use in the agrochemical industry, where it can be employed in the synthesis of pesticides, herbicides, and other agricultural chemicals. Its reactive nature allows for the development of molecules with targeted effects on pests or weeds.
Safety Precautions:
Due to the highly reactive nature of 2-(BROMOMETHYL)-1-NITRO-3-(TRIFLUOROMETHYL)BENZENE, it is crucial to handle this compound with care. Proper safety measures, including the use of personal protective equipment and adherence to laboratory safety protocols, should be taken to minimize potential hazards.
Check Digit Verification of cas no
The CAS Registry Mumber 133605-26-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,3,6,0 and 5 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 133605-26:
(8*1)+(7*3)+(6*3)+(5*6)+(4*0)+(3*5)+(2*2)+(1*6)=102
102 % 10 = 2
So 133605-26-2 is a valid CAS Registry Number.
InChI:InChI=1/C8H5BrF3NO2/c9-4-5-6(8(10,11)12)2-1-3-7(5)13(14)15/h1-3H,4H2
133605-26-2Relevant articles and documents
Photoactivatable Sensors for Detecting Mobile Zinc
Goldberg, Jacob M.,Wang, Fang,Sessler, Chanan D.,Vogler, Nathan W.,Zhang, Daniel Y.,Loucks, William H.,Tzounopoulos, Thanos,Lippard, Stephen J.
, p. 2020 - 2023 (2018)
Fluorescent sensors for mobile zinc are valuable for studying complex biological systems. Because these sensors typically bind zinc rapidly and tightly, there has been little temporal control over the activity of the probe after its application to a sample. The ability to control the activity of a zinc sensor in vivo during imaging experiments would greatly improve the time resolution of the measurement. Here, we describe photoactivatable zinc sensors that can be triggered with short pulses of UV light. These probes are prepared by functionalizing a zinc sensor with protecting groups that render the probe insensitive to metal ions. Photoinduced removal of the protecting groups restores the binding site, allowing for zinc-responsive changes in fluorescence that can be observed in live cells and tissues.
INHIBITORS OF CYTOSOLIC PHOSPHOLIPASE A2
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Page/Page column 53, (2008/06/13)
This invention provides chemical inhibitors of the activity of various phospholipase enzymes, particularly cytosolic phospholipase A2 enzymes (cPLA2), more particularly including inhibitors of cytosolic phospholipase A2 alpha enzymes (cPLAα). In some embodiments, the inhibitors have the Formula I: wherein the constituent variables are as defined herein.
Resist materials
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, (2008/06/13)
A class of resist compositions sensitive to deep ultraviolet radiation includes a resin sensitive to acid and a composition that generates acid upon exposure to such radiation. A group of nitrobenzyl materials is particularly suitable for use as the acid generator.
