133671-30-4

Upstream product

• 403-42-9 1-(4-fluorophenyl)ethanone 
• 88-17-5 2-(trifluoromethyl)benzenamine 

Downstream Products

• 103914-43-8 4-chloro-2-(4-fluorophenyl)quinoline 
• 147218-08-4 4-tert-butoxy-2-(4-fluorophenyl)quinoline 
• 313833-23-7 N-[4-(dimethylamino)butyl]-2-(4-fluorophenyl)quinolin-4-amine 
• 510755-23-4 N-[3-(dimethylamino)propyl]-(4-fluorophenyl)quinolin-4-amine 
• 924621-12-5 N-(6-chlorohexyl)-2-(4-fluorophenyl)quinolin-4-amine 
• 924621-09-0 N-(6-hydroxyhexyl)-2-(4-fluorophenyl)quinolin-4-amine 
• 924621-11-4 N-(4-chlorobutyl)-2-(4-fluorophenyl)quinolin-4-amine 
• 924621-08-9 N-(4-hydroxybutyl)-2-(4-fluorophenyl)quinolin-4-amine 
• 133671-46-2 N-<2-(dimethylamino)ethyl>-2-(4-fluorophenyl)quinolin-4-amine 

Relevant academic research and scientific papers

Synthesis of Fluoro and Trifluoromethyl Derivatives of 2-Phenylquinolin-4-ol

A tert-butoxide base-mediated cyclization of fluoro- and trifluoromethyl-substituted Schiff bases 12-19 produces 4-tert-butoxyquinolines 23-30 which are hydrolyzed to quinolin-4-ols 31-38.

Synthesis and quantitative structure-activity relationship analysis of 2-(aryl or heteroaryl)quinolin-4-amines, a new class of anti-HIV-1 agents

Thirty-eight 2-(aryl or heteroaryl)quinolin-4-amines, N,N-disubstituted, N-monosubstituted, and without a substituent at the amino group have been synthesized with use of novel chemistries developed by us recently. Some of these derivatives show anti-HIV-