133703-65-8Relevant academic research and scientific papers
Towards a Series of Chiral Primary Amines Bearing α-Amino Acid and Benzo[d]imidazole Pendants, and Their Application in Asymmetric Aldol Reactions
Mohite, Pravinkumar Hansraj,Drabina, Pavel,Bure?, Filip
, p. 1613 - 1622 (2017/03/21)
A straightforward reaction path towards chiral primary amines bearing α-amino acid and benzo[d]imidazole pendants has been developed. Six starting essential α-amino acids were converted into the target chiral amines in a four-step synthesis. The prepared
Benzo[ d ]imidazole and aliphatic α-amino acid derived primary amines in asymmetric aldol reactions
Mohite, Pravinkumar Hansraj,Drabina, Pavel,Bure?, Filip
, p. 491 - 494 (2014/03/21)
Starting from essential α-amino acids, four new benzo[d]imidazole and alkyl-chain-substituted primary amines were synthesized. The reaction sequence involves activation of the Boc-amino acid carboxylic acid, reaction with o-phenylenediamine, and subsequen
Thioacylating Agents. Use of Thiobenzimidazolone Derivatives for the Preparation of Thiotuftsin Analogs.
Zacharie, Boulos,Sauve, Gilles,Penney, Christopher
, p. 10489 - 10500 (2007/10/02)
The properties and characteristic reactions of thioacylating reagents 1 are described.These reagents are able to introduce thioamide linkages into a growing peptide at a specific site in the sequence.The generality and efficiency of this methodology is demonstrated by the synthesis of the three monothioanalogues of tuftsin.
