133725-75-4Relevant academic research and scientific papers
Synthesis of C-Functionalized trans-Cyclohexyldiethylenetriaminepenta-acetic Acids for Labelling of Monoclonal Antibodies with the Bismuth-212 α-Particle Emitter
Brechbiel, Martin W.,Gansow, Otto A.
, p. 1173 - 1178 (2007/10/02)
Several C-functionalized cyclohexyldiethylenetriaminepenta-acetic acid derivatives have been prepared from (+/-)-4-nitrophenylalanine and (+/-)-trans-cyclohexane-1,2-diamine to produce two sets of diastereoisomeric enantiomers.A modification of this synth
An Effective Chelating Agent for Labelling of Monoclonal Antibody with 212Bi for &α-Particle Mediated Radioimmunotherapy
Brechbiel, Martin W.,Pippin, C. Greg,McMurry, Thomas J.,Milenic, Diane,Roselli, Mario,et al.
, p. 1169 - 1170 (2007/10/02)
The ligand N--(+/-)trans-1,2-diaminocyclohexane-N,N',N''-pentaacetic acid has been synthesized and linked to lgG and to monoclonal antibody B72.3 and labelled with 206Bi and 212Bi to demonstrate the in vivo stabil
