133728-83-3

Upstream product

• 56183-63-2 bis(diisopropylamino)chlorophosphine 
• 67219-55-0 4-N-Benzoyl-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)cytidine 

Downstream Products

• 116003-04-4 N₄-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine-3-O-[O-(2-cyanoethyl)-N,N-(diisopropyl)]phosphoramidite 
• 860303-70-4 N₄-benzoyl-5'-O-(4,4'-dimethoxytrityl)-3'-O-[2-(N-formyl-N-methylamino)ethoxy]-(N,N-diisopropylamino)phosphinyl-2'-deoxycytidine 

Relevant academic research and scientific papers

PHOSPHORAMIDITE BUILDING BLOCKS FOR SUGAR-CONJUGATED OLIGONUCLEOTIDES

Novel nucleoside phosphoramidite building blocks for preparation of synthetic oligonucleotides containing at least one phosphotriester linkage conjugated to a monosaccharide and synthetic processes for making the same are disclosed. Furthermore, oligomeri

(2-Acetoxyphenoxy)ethyl (APOe) as a phosphate protecting group in solid-phase synthesis of oligonucleotides via the phosphoramidite approach

The (2-Acetoxyphenoxy)ethyl (APOe) group could be an alternative to the conventional 2-cyanoethyl group for phosphate protection in solid-phase oligonucleotide synthesis to circumvent DNA alkylation by acrylonitrile generated under basic condition. This g

Method of preparing phosphoramidites

Improved methods for preparation of phosphoramidite compounds are disclosed. The phosphoramidites are useful, for example, for the preparation of oligonucleotides by solid state oligonucleotide synthetic regimes.