133736-02-4Relevant articles and documents
Preparation, derivatization with trimethylsilyldiazomethane, and GC/MS analysis of a "pool" of alkyl methylphosphonic acids for use as qualitative standards in support of counterterrorism and the chemical weapons convention
Crenshaw, Michael D.,Cummings, David B.
, p. 1009 - 1018 (2007/10/03)
There are hundreds of nerve agents in the class of alkyl methylphosphonofluoridates covered by Schedule 1 of the CWC (Chemical Weapons Convention). Hydrolysis of these sarin-like nerve agents results in an equal number of alkyl methylphosphonic acids. These alkyl methylphosphonic acids are persistent and provide good evidence of specific agent production or use. In order to support the CWC and counterterrorism activities, it is desirable to have ready access to each of these hydrolysis products for use as qualitative standards. A means for simultaneously producing multiple alkyl methylphosphonates from methylphosphonic acid and the corresponding alcohols was developed. Derivatization of these alkyl methylphosphonic acids with trimethylsilyldiazomethane yields the corresponding methyl esters which are suitable for GC/MS analysis.
BISPHOSPHONIC COMPOUNDS. IV. PREPARATION AND IDENTIFICATION OF MIXED TETRAALKYL METHYLENE- AND (DICHLOROMETHYLENE)BISPHOSPHONATES BY NMR SPECTROSCOPIC, MASS SPECTROMETRIC AND X-RAY CRYSTALLOGRAPHIC STUDIES
Vepsaelaeinen, Jouko,Pohjala, Esko,Nupponen, Heikki,Vainiotalo, Pirjo,Ahlgren, Markku
, p. 183 - 204 (2007/10/02)
The chemisty of 28 mixed tetraalkyl methylene- and (dichloromethylene)bisphosphonates, (R1O)(R2O)P(O)CX2P(O)(OR3)(OR4), where R1 = Et, Allyl, CH=CHMe, Pri, Bu, But, Hex, Ph, Bn or octadecyl, R2 = Me, Et, Pri, Bu, But
