13374-30-6

Basic information

• Product Name: trans-2-Aminocyclo hexanol hydrochloride
• Synonyms: [1S,2S]-Trans--Aminocyclohexanol hydrochloride;(1S,2S)-trans-2-Aminocyclohexanol hydrochloride;Trans (1S,2S)-2-amino-cyclohexanol hydrochloride;Cyclohexanol, 2-aMino-,hydrochloride (1:1), (1S,2S)-;(1S,2S)-2-AMinocylohexanol hydrochloride;(1S,2S)-2-aMinocyclohexan-1-ol hydrochloride;cis-2-aMinocyclohexan-1-ol hydrochloride;2-AMino-cyclohexanol.HCl
• CAS NO: 13374-30-6
• Molecular Formula: C₆H₁₃NO*ClH
• Molecular Weight: 151.6345
• Product Categories: cyclic compounds
• Mol File: 13374-30-6.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 201.1 °C at 760 mmHg
• Flash Point: 75.4 °C
• Appearance: /
• Vapor Pressure: 0.0773mmHg at 25°C
• Storage Temp.: 2-8°C
• CAS DataBase Reference: trans-2-Aminocyclo hexanol hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: trans-2-Aminocyclo hexanol hydrochloride(13374-30-6)
• EPA Substance Registry System: trans-2-Aminocyclo hexanol hydrochloride(13374-30-6)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26
• WGK Germany: 3
• Hazardous Substances Data: 13374-30-6(Hazardous Substances Data)

Usage

Chemical Properties

White crystalline powder

InChI:InChI=1/C6H13NO.ClH/c7-5-3-1-2-4-6(5)8;/h5-6,8H,1-4,7H2;1H/t5-,6-;/m0./s1

Upstream product

• 221110-45-8 1-azido-2-(trimethylsiloxy)cyclohexane 
• 202461-26-5 trans-2-acetamidocyclohexyl acetate 
• 931-15-7 (1S,2S)-trans-2-aminocyclohexanol 
• 106729-82-2 (1R,2R,6R)-2-Bromo-6-[3H-isobenzofuran-(1Z)-ylideneamino]-cyclohexanol 
• 822-67-3 Cyclohex-2-enol 
• 106729-82-2 1,2-trans-1,6-cis-2-bromo-6-(1,3-dihydroisobenzofuran-1-ylideneamino)-cyclohexanol 
• 106729-81-1 o-cyclohex-2-enylcarbamoylbenzyl alcohol 
• 1541-26-0 2-cyclohex-2-enyl-isoindole-1,3-dione 
• 116429-76-6 ((3aS,4S,7aS)-4-Bromo-2-ethoxy-2-phenyl-hexahydro-benzooxazol-3-yl)-phenyl-methanone 
• 106729-73-1 cyclohex-2-enyl-N-benzoylbenzimidate 
• 106729-74-2 1,2-cis-2,3-trans-2-benzamido-3-bromocyclohexyl benzoate 
• 3413-44-3 (R)-2-cyclohexen-1-ol 
• 106729-83-3 (1S,2R)-2-[3H-Isobenzofuran-(1Z)-ylideneamino]-cyclohexanol 
• 106729-83-3 1,2-cis-(1,3-dihydroisobenzofuran-1-ylideneamino)cyclohexanol 

Downstream Products

• 38436-56-5 cis-β-Hydroxycyclohexyl-trimethylammonium-iodid 
• 190848-36-3 (1S,2S)-N-(2-hydroxycyclohexyl)acetamide 
• 74023-84-0 N¹-(1'S,2'-S)-2'-hydroxycyclohexylnicotinamide chloride 
• 364753-67-3 C₂₂H₃₀N₄O₆ 
• 364753-66-2 C₂₂H₃₀N₄O₆ 
• 821801-07-4 2,2-Difluoro-3-hydroxy-dodecanoic acid ((1S,2S)-2-hydroxy-cyclohexyl)-amide 
• 823177-21-5 (1S,2S)-N-(2-hydroxycyclohexyl)butyramide 

Relevant articles and documents

Asymmetric acylation reactions catalyzed by conformationally biased octapeptides

Octapeptides capable of adopting β-hairpin conformations have been found to function as efficient catalysts for the kinetic resolution of certain racemic secondary alcohols. Parallel solid phase synthesis of a series of peptides with the common feature of the D-Pro-Gly sequence at the turn region (i+3 to i+4) was carried out to yield a family of octapeptide catalysts. The peptides were then screened for their efficiency in a number of enantioselective acylation reactions. (C) 2000 Elsevier Science Ltd.

Stereocontrolled Preparation of Cyclohexane Amino Alcohols Utilising a Modified Mitsunobu Reaction

A method for the introduction of amino groups into aliphatic systems is described.Cyclohex-2-enol reacts with aromatic diacylamines under Mitsunobu reaction conditions to give either N-alkylated or O-alkylated products in a controlled, predictable manner.

NEW ROUTES TO CIS-1,2-HYDROXYAMINES AND RELATED SYSTEMS

Use of modified Mitsunobu reactions followed by intramolecular cyclisations have been used to prepare cis-1,2-hydroxyamines, cis-1,3-hydroxyamines, 1,2,3-dihydroxyamines and 1,2,3-diaminoalcohols from allylic alcohols