133747-59-8Relevant articles and documents
A2Badenosine receptor antagonists: Design, synthesis and biological evaluation of novel xanthine derivatives
Basu, Sujay,Barawkar, Dinesh A.,Ramdas, Vidya,Waman, Yogesh,Patel, Meena,Panmand, Anil,Kumar, Santosh,Thorat, Sachin,Bonagiri, Rajesh,Jadhav, Dilip,Mukhopadhyay, Partha,Prasad, Vandna,Reddy, B. Srinivasa,Goswami, Arnab,Chaturvedi, Sandhya,Menon, Suraj,Quraishi, Azfar,Ghosh, Indraneel,Dusange, Sushant,Paliwal, Shalini,Kulkarni, Abhay,Karande, Vikas,Thakre, Rhishikesh,Bedse, Gaurav,Rouduri, Sreekanth,Gundu, Jayasagar,Palle, Venkata P.,Chugh, Anita,Mookhtiar, Kasim A.
, p. 986 - 996 (2017/02/12)
A2BAdoR is a low affinity adenosine receptor that functions by Gs mediated elevation of cAMP and subsequent downstream signaling. The receptor has been implicated in lung inflammatory disorders like?COPD and asthma. Several potent and selective
Phenylcarboxylic acid derivatives having hetero ring
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, (2008/06/13)
Phenylcarboxylic acid derivatives having a hetero ring in the substituent of the formula: STR1 wherein R1 is halogen, alkyl, cycloalkyl, hydroxy, alkoxy, phenoxy which has a substituent selected from halogen and alkyl, carboxyl, alkylsulfonyloxy, phenylsulfonyloxy optionally substituted by halogen, alkylsulfonyloxyalkoxy, amino, alkanoylamino, benzoylamino, alkenyloxy, phenylalkoxyalkoxy, hydroxyalkoxy, phenylalkoxy having optionally 1 to 3 substituents selected from halogen, alkyl and alkoxy, halogenoalkyl, cycloalkyloxy optionally substituted by hydroxy, alkoxy substituted by cycloalkyl having optionally hydroxy substituent, imidazolylalkyl or imidazolylalkoxy; k is 0 or 1 to 3; or (R1)k is alkylenedioxy; A is alkylene or alkylenoxy; l is 0 or 1; B is methylene or carbonyl; m is 0 or 1; D is alkylene; E is alkylene or alkenylene; n is 0 or 1; and R2 is hydrogen or alkyl, or a salt thereof, which have fatty acid synthesis-inhibitory activity, cholesterol synthesis-inhibitory activity and are useful as antilipidemic agent, prophylactic and treating agent of arteriosclerosis, prophylactic and treating agent of obesity, antidiabetics.