1337551-93-5

Basic information

• Product Name: (2R,3S)-1'-benzyl-3-(4-nitrophenyl)-3H-spiro[furan-2,3'-indoline]-2',5(4H)-dione
• Synonyms: (2R,3S)-1'-benzyl-3-(4-nitrophenyl)-3H-spiro[furan-2,3'-indoline]-2',5(4H)-dione
• CAS NO: 1337551-93-5
• Molecular Weight: 414.417
• Mol File: 1337551-93-5.mol

Chemical Properties

• CAS DataBase Reference: (2R,3S)-1'-benzyl-3-(4-nitrophenyl)-3H-spiro[furan-2,3'-indoline]-2',5(4H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3S)-1'-benzyl-3-(4-nitrophenyl)-3H-spiro[furan-2,3'-indoline]-2',5(4H)-dione(1337551-93-5)
• EPA Substance Registry System: (2R,3S)-1'-benzyl-3-(4-nitrophenyl)-3H-spiro[furan-2,3'-indoline]-2',5(4H)-dione(1337551-93-5)

Safety Data

• Hazardous Substances Data: 1337551-93-5(Hazardous Substances Data)

Upstream product

• 1734-79-8 3-(4-nitrophenyl)-2-propenal 
• 1217-89-6 1-benzylisatin 
• 92552-73-3 1-benzyl-3-hydroxyindolin-2-one 
• 16642-79-8 3-(4-nitrophenyl)propionic acid 

Relevant articles and documents

An NHC-catalyzed in situ activation strategy to β-functionalize saturated carboxylic acid: An enantioselective formal [3+2] annulation for spirocyclic oxindolo-γ-butyrolactones

An in situ NHC-catalyzed activation strategy to β-functionalize saturated carboxylic acid was developed. This asymmetric formal [3+2] annulation could deliver spirocyclic oxindolo-γ-butyrolactones from saturated carboxylic acid and isatin in good yields with high to excellent enantioselectivities. The easy availability of the starting materials, direct installation of functional units at unreactive carbon atom and the convergent assembly make this protocol attractive in the field of organic synthesis. Top cat: An in situ N-heterocyclic carbene (NHC)-catalyzed activation strategy to β-functionalize saturated carboxylic acid was developed (see scheme). This asymmetric formal [3+2] annulation delivered spirocyclic oxindolo-γ-butyrolactones from saturated carboxylic acid and isatin in good yields with high to excellent enantioselectivities. The availability of the starting materials, direct installation of functional units at unreactive carbon atom and the convergent assembly make this protocol attractive for organic synthesis.

N-Heterocyclic carbene-catalyzed oxidative [3 + 2] annulation of dioxindoles and enals: cross coupling of homoenolate and enolate

The N-heterocyclic carbene-catalyzed oxidative [3 + 2] annulation of dioxindole and enals was developed, giving the corresponding spirocyclic oxindole-γ-lactones in good yields with high to excellent diastereo- and enantioselectivities. The challenging al

Highly diastereo- and enantioselective NHC-catalyzed [3+2] annulation of enals and isatins

The chiral N-heterocyclic carbene bearing a proximal hydroxy group derived from l-pyroglutamic acid was found to be an efficient catalyst for the [3+2] annulation of enals and isatins to give the corresponding spirocyclic oxindolo-γ-butyrolactones in good yield with good diastereo- and enantioselectivities. The Royal Society of Chemistry 2011.