1337561-46-2

Upstream product

• 1337561-42-8 5-(anthracen-9-yl)-3-(4-chlorophenyl)-4, 5-dihydro-1H-pyrazole 
• 103-72-0 phenyl isothiocyanate 
• 57076-91-2 (E)-3-(anthracen-10-yl)-1-(4-chlorophenyl)prop-2-en-1-one 
• 99-91-2 para-chloroacetophenone 
• 642-31-9 9-anthracene aldehyde 

Relevant academic research and scientific papers

Synthesis and biological activity of some new pyrazoline and pyrimidine derivatives

New series of pyrazoline 3-aryl-4,5-dihydro-1H-pyrazole-1-carbaldehydes (4-6), (aryl-4,5-dihydro-1H-pyrazol-1-yl)ethanones (9-11) and 3-aryl-4,5-dihydro-1H-pyrazoles (24 and 25) were synthesized by reacting chalcones (1-3) with hydrazine hydrate in either formic acid, acetic acid or ethanol, respectively. Also, new 6-arylpyrimidin-2-amine derivatives (32-34) were synthesized from the same chalcones. The structures of the newly synthesized compounds were established on the basis of IR, 1H NMR, 13C NMR, mass spectral data and elemental analyses. The compounds were evaluated for their antibacterial and antifungal activities. Three heterocycles showed relevant activity against C. albicans and some compounds also showed activity against E. coli.