133762-16-0

Basic information

• Product Name: ethyl (4-oxo-3,4-dihydrocinnolin-2(1H)-yl)acetate
• CAS NO: 133762-16-0
• Molecular Formula: C₁₂H₁₄N₂O₃
• Molecular Weight: 234.2512
• Mol File: 133762-16-0.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 366.5°C at 760 mmHg
• Flash Point: 175.4°C
• Density: 1.207g/cm³
• Vapor Pressure: 1.46E-05mmHg at 25°C
• Refractive Index: 1.544
• CAS DataBase Reference: ethyl (4-oxo-3,4-dihydrocinnolin-2(1H)-yl)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl (4-oxo-3,4-dihydrocinnolin-2(1H)-yl)acetate(133762-16-0)
• EPA Substance Registry System: ethyl (4-oxo-3,4-dihydrocinnolin-2(1H)-yl)acetate(133762-16-0)

Safety Data

• Hazardous Substances Data: 133762-16-0(Hazardous Substances Data)

Upstream product

• 105-36-2 ethyl bromoacetate 
• 137195-33-6 4-oxo-1,2,3,4-tetrahydrocinnoline hydrochloride 

Relevant articles and documents

Synthesis and action on the central nervous system of some N2-substituted cinnoline derivatives

Alkylation of 4-hydroxycinnolines using ethyl bromoacetate resulted in N2-substituted acetic acids. These acids were converted to esters and amides. Some of the obtained acids were reduced with zinc dust to give 4-oxo-1,2,3,4-tetrahydro-2-cinnolineacetic acids. Several of the compounds were tested for their effect on central nervous system.