133789-65-8

Basic information

• Product Name: (R)-3,4-Methylenedioxystyreneoxide
• Synonyms: (R)-3,4-Methylenedioxystyreneoxide
• CAS NO: 133789-65-8
• Molecular Formula: C₉H₈O₃
• Molecular Weight: 164.15802
• Mol File: 133789-65-8.mol
• Article Data: 9

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (R)-3,4-Methylenedioxystyreneoxide(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-3,4-Methylenedioxystyreneoxide(133789-65-8)
• EPA Substance Registry System: (R)-3,4-Methylenedioxystyreneoxide(133789-65-8)

Safety Data

• Hazardous Substances Data: 133789-65-8(Hazardous Substances Data)

Usage

General Description

(R)-3,4-Methylenedioxystyreneoxide, also known as safrole epoxide, is a chemical compound derived from the sassafras tree and other plants. It is a type of epoxide, which is a class of organic compounds containing a three-membered ring formed by the attachment of two carbon atoms to the same oxygen atom. (R)-3,4-Methylenedioxystyreneoxide is commonly used in the synthesis of various drugs and pharmaceuticals, as well as in the production of fragrances and flavoring agents. It is also a precursor to the illegal drug MDMA (ecstasy). The compound has raised concerns due to its potential to be converted into the illegal substance MDMA, and the use and distribution of (R)-3,4-Methylenedioxystyreneoxide is heavily regulated in many countries.

Upstream product

• 133789-63-6 (R,R)-1-<3',4'-(methylenedioxy)phenyl>-2-(p-tolylsulfinyl)ethan-1-ol 
• 133789-62-5 (R)-1-<3',4'-(methylenedioxy)phenyl>-2-(p-tolylsulfinyl)ethan-1-one 
• 326-56-7 methyl 3,4-methylenedioxybenzoate 
• 133789-64-7 (R)-1-<3',4'-(methylenedioxy)phenyl>-2-(p-tolylthio)ethan-1-ol 
• 287204-24-4 1-iodo-3-[3,4-(methylenedioxy)phenyl]propan-2-ol 
• 7315-32-4 5-vinyl-1,3-benzodioxole 
• 120-57-0 piperonal 
• 75-18-3 dimethylsulfide 
• 77-78-1 dimethyl sulfate 
• 2181-42-2 trimethylsulphonium iodide 
• 6814-64-8 methylenedimethyl sulfurane 

Downstream Products

• 120-57-0 piperonal 
• 136631-31-7 Ethyl (3R*,3aS*,6aR*)-Hexahydro-3a-(1,3-benzodioxol-5-yl)-1-(1'(S*)-phenylethyl)-5-oxocyclopentisoxazole-3-carboxylate 
• 136631-31-7 C₂₇H₃₁NO₅S₂ 
• 136631-31-7 Ethyl (3β,3aα,6aα)-Hexahydro-3a-(1,3-benzodioxol-5-yl)-1-(1-phenylethyl)-5-oxocyclopentisoxazole-3-carboxylate, 1,3-Propanediyl Dithioketal 
• 136631-31-7 C₂₇H₃₁NO₅S₂ 
• 136631-29-3 C₂₇H₃₁NO₅S₂ 
• 136631-33-9 C₂₇H₃₁NO₅S₂ 
• 136631-36-2 Hexahydro-(3R*,3aS*,6aR*)-3a-(1,3-benzodioxol-5-yl)-3-(benzoyloxy)-1-(1'(S*)-phenylethyl)cyclopentapyrrole-2,5(1H)-dione, 5-(1,3-Propanediyl dithioketal) 
• 136631-34-0 Hexahydro-(3R*,3aS*,6aR*)-3-acetoxy-3a(-1,3-benzodioxol-5-yl)-1-(1'(S*)-phenylethyl)cyclopentapyrrole-2,5(1H)-dione, 5-(1,3-Propanediyl dithioketal) 
• 136631-37-3 Hexahydro-(3R*,3aS*,6aR*)-3a-(1,3-benzodioxol-5-yl)-3-(benzyloxy)-1-(1'(S*)-phenylethyl)cyclopentapyrrole-2,5(1H)-dione 
• 136631-35-1 C₂₅H₂₇NO₄S₂ 
• 80860-21-5 1-Benzo[1,3]dioxol-5-yl-2-(1-phenyl-ethylamino)-ethanol 
• 80860-20-4 1-Benzo[1,3]dioxol-5-yl-2-phenethylamino-ethanol 
• 6543-34-6 benzo[1,3]dioxol-5-yl-acetaldehyde 

Relevant articles and documents

Envirocat (K10-MX)-catalyzed regioselective transformation of alkenes into iodohydrins and β-iodo ethers and further conversion of iodohydrins to epoxides using Al2O3-Na2Co3 under MWI

Commercial K10 clay was converted to extremely efficient and environmentally friendly catalyst K10-MX for the preparation of iodohydrins and β-iodo ethers from alkenes (terminal as well as internal) using microwave irradiation. This method was further extended for the conversion of alkenes to epoxides via iodohydrin intermediate in a one-pot reaction system. Copyright Taylor & Francis Group, LLC.

Ethanolamine derivatives having sympathomimetic and anti-pollakiuria activities

This invention relates to new ethanolamine derivatives having gut selective sympathomimetic and anti-pollakiuria activities and represented by the general formula [I]: STR1 wherein R1 is aryl or a heterocyclic group, each of which may be substituted with halogen, etc., R2 is hydrogen, halogen, nitro, hydroxy, lower alkyl optionally substituted with acyl, lower alkenyl optionally substituted with acyl, lower alkoxy optionally substituted with acyl, or amino optionally substituted with acyl(lower)alkyl, R3 is hydrogen, an N-protective group, or lower alkyl optionally substituted with lower alkylthio, n is an integer of 0 to 3, and a heavy solid line means a single bond or a double bond, provided that when n is 1, then 1) R1 is a condensed aromatic hydrocarbon group or a heterocyclic group, each of which may be substituted with halogen, etc., and the like, and pharmaceutically acceptable salts thereof to processes for the preparation thereof and to a pharmaceutical composition comprising the same.

Enanthioselective synthesis of both enantioners of a isoproterenol analogue and of di-O-pivaloylepinephrine

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