1337933-93-3Relevant academic research and scientific papers
Palladium-catalyzed aryl iodide carbonylation as a route to imidazoline synthesis: Design of a five-component coupling reaction
Bontemps, Sebastien,Quesnel, Jeffrey S.,Worrall, Kraig,Arndtsen, Bruce A.
supporting information; experimental part, p. 8948 - 8951 (2011/10/19)
Take five: A new method employing aryl halide carbonylation to directly access heterocycles has been described (see scheme). In a single palladium-catalyzed reaction the catalyst mediates two consecutive carbonylation steps, thereby converting five components (aryl iodide, two units imine, and two units CO) into an imidazoline ring.
