1337962-17-0Relevant academic research and scientific papers
Synthesis and biological evaluation of gemfibrozil chiral analogues as potential PPARα agonists
De Filippis, Barbara,Giampietro, Letizia,Giancristofaro, Antonella,Ammazzalorso, Alessandra,Fantacuzzi, Marialuigia,Maccallini, Cristina,Petruzzelli, Michele,Amoroso, Rosa
experimental part, p. 154 - 158 (2012/02/04)
Two series of gemfibrozil chiral analogues were synthesized and evaluated for their agonistic activity on PPARα receptor, belonging to the transcription factor family. A simple method to synthesize ureidic and thioureidic fibrates is described. Their abil
