1337978-99-0Relevant articles and documents
One-pot synthesis of indole-fused scaffolds via gold-catalyzed tandem annulation reactions of 1,2-bis(alkynyl)-2-en-1-ones with indoles
Xie, Xin,Du, Xiangwei,Chen, Yifeng,Liu, Yuanhong
, p. 9175 - 9181 (2011/12/15)
The gold-catalyzed tandem cyclization of 1,2-bis(alkynyl)-2-en-1-ones with indoles offers an efficient and straightforward route to indole-fused polycyclic systems. The process is realized through a cascade carbonyl-yne cyclization/Friedel-Crafts/indole-yne cyclization sequence catalyzed by a single-pot catalyst of gold.