1338064-74-6

Basic information

• Product Name: 1-(4-(trifluoromethyl)-2-(piperidin-1-yl)benzyl)-3-(2,3-dihydro-2-oxobenzo[d]oxazol-7-yl)urea
• Synonyms: 1-(4-(trifluoromethyl)-2-(piperidin-1-yl)benzyl)-3-(2,3-dihydro-2-oxobenzo[d]oxazol-7-yl)urea
• CAS NO: 1338064-74-6
• Molecular Weight: 434.418
• Mol File: 1338064-74-6.mol

Chemical Properties

• CAS DataBase Reference: 1-(4-(trifluoromethyl)-2-(piperidin-1-yl)benzyl)-3-(2,3-dihydro-2-oxobenzo[d]oxazol-7-yl)urea(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-(trifluoromethyl)-2-(piperidin-1-yl)benzyl)-3-(2,3-dihydro-2-oxobenzo[d]oxazol-7-yl)urea(1338064-74-6)
• EPA Substance Registry System: 1-(4-(trifluoromethyl)-2-(piperidin-1-yl)benzyl)-3-(2,3-dihydro-2-oxobenzo[d]oxazol-7-yl)urea(1338064-74-6)

Safety Data

• Hazardous Substances Data: 1338064-74-6(Hazardous Substances Data)

Upstream product

• 935518-09-5 (4-(trifluoromethyl)-2-(piperidin-1-yl)phenyl)-methanamine 
• 6358-08-3 4-chloro-6-nitro-2-aminophenol 
• 689141-78-4 2-(1-piperidinyl)-4-(trifluoromethyl)-benzonitrile 
• 1338065-39-6 C₁₄H₁₅F₃N₂O 
• 81282-60-2 7-aminobenzo[d]oxazol-2(3H)-one 
• 1813-33-8 2-chloro-4-trifluoromethyl-benzonitril 
• 110-89-4 piperidine 
• 811810-67-0 5-chloro-7-nitrobenzo[d]oxazol-2(3H)-one 

Relevant articles and documents

"TRPV1 VANILLOID RECEPTOR ANTAGONISTS WITH A BICYCLIC PORTION"

The invention discloses compounds of formula I wherein Y is a group of formula A, B, C, D, or E: and W, Q, n, R1, R2, R3, U1-U5, J and K have the meanings given in the description. The compounds of formula I are TRPV1 antagonists and are useful as active

TRPV1 vanilloid receptor antagonists with a bicyclic portion

The invention discloses compounds of formula I wherein Y s selected from a group of formula and W, Q, n, R1, R2, R3, U1-U5 have the meanings given in the description. The compounds of formula I are TRPV1 antagonists and are useful as active ingredients of pharmaceutical compositions for the treatment of pain and other conditions ameliorated by the inhibition of the vanilloid receptor TRPV1. 1.