1338085-77-0Relevant articles and documents
Synthesis of 3,7-disubstituted imipramines by palladium-catalysed amination/cyclisation and evaluation of their inhibition of monoamine transporters
Christensen, Helle,Schjoth-Eskesen, Christina,Jensen, Marie,Sinning, Steffen,Jensen, Henrik H.
, p. 10618 - 10627 (2011)
We describe a novel approach for the synthesis of a series of 3,7-difunctionalised symmetric and unsymmetrical analogues of the tricyclic antidepressant (TCA) imipramine, which uses a key palladium-catalysed amination/cyclisation of an ester-functionalise