1338225-65-2

Upstream product

• 944052-53-3 (3R)-3-[2-(4-methylphenyl)-2-oxoethyl]-2-[(1S,5R)-5,8,8-trimethyl-2-oxo-3-oxabicyclo[3.2.1]octane-1-carbonyl]-2,3-dihydroisoindol-1-one 
• 1338225-77-6 (3R)-3-[(2S)-2-hydroxy-2-(4-methylphenyl)ethyl]-2,3-dihydro-1H-isoindol-1-one 
• 1338225-80-1 {(1R)-2-[(1R)-3-oxo-2,3-dihydro-1H-isoindol-1-yl]-1-(4-methylphenyl)ethyl} benzoate 
• 1338225-81-2 (3R)-3-[(2R)-2-hydroxy-2-(4-methylphenyl)ethyl]-2,3-dihydro-1H-isoindol-1-one 
• 1338225-86-7 (3R,4aR)-3-(4-methylphenyl)-3,4,4a,9-tetrahydro-1,3-oxazino[4,3-a]isoindole 
• 1338320-09-4 (1R)-2-[(1R)-2-methyl-2,3-dihydro-1H-isoindol-1-yl]-1-(4-methylphenyl)ethanol 
• 1338225-74-3 (3R)-3-[(2S)-2-hydroxy-2-(4-methylphenyl)ethyl]-2-[(1S,5R)-5,8,8-trimethyl-2-oxo-3-oxabicyclo[3.2.1]octane-1-carbonyl]-2,3-dihydroisoindol-1-one 

Relevant academic research and scientific papers

Synthesis of a series of γ-amino alcohols comprising an N-methyl isoindoline moiety and their evaluation as NMDA receptor antagonists

We report a series of new stereoisomeric γ-amino alcohols comprising an N-methyl isoindoline moiety as ligands for the ifenprodil binding site of the NMDA receptor. Among the four series of stereoisomers, 8a-c, 9a-c, 10a-c, and 11a-c, synthesised, the hig