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1338240-99-5

5-(5-bromo-2-methylbenzylidene)-3,3-dimethylpiperidin-4-one is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1338240-99-5 Structure

  • Basic information

    1. Product Name: 5-(5-bromo-2-methylbenzylidene)-3,3-dimethylpiperidin-4-one
    2. Synonyms:
    3. CAS NO:1338240-99-5
    4. Molecular Formula:
    5. Molecular Weight: 308.218
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1338240-99-5.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 5-(5-bromo-2-methylbenzylidene)-3,3-dimethylpiperidin-4-one(CAS DataBase Reference)
    10. NIST Chemistry Reference: 5-(5-bromo-2-methylbenzylidene)-3,3-dimethylpiperidin-4-one(1338240-99-5)
    11. EPA Substance Registry System: 5-(5-bromo-2-methylbenzylidene)-3,3-dimethylpiperidin-4-one(1338240-99-5)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1338240-99-5(Hazardous Substances Data)

1338240-99-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1338240-99-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,3,8,2,4 and 0 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1338240-99:
(9*1)+(8*3)+(7*3)+(6*8)+(5*2)+(4*4)+(3*0)+(2*9)+(1*9)=155
155 % 10 = 5
So 1338240-99-5 is a valid CAS Registry Number.

1338240-99-5Downstream Products

1338240-99-5Relevant articles and documents

Design, Synthesis, and Cytotoxicity of Novel 3-Arylidenones Derived from Alicyclic Ketones

Satam, Vijay,Bandi, Ravi K.,Behera, Ajaya K.,Mishra, Bijay K.,Tzou, Samuel,Brockway, Olivia,Babu, Balaji,Zeller, Matthias,Westbrook, Cara,Mooberry, Susan L.,Lee, Moses,Pati, Hari

, p. 700 - 708 (2012/04/04)

Forty-four novel chalcone-inspired analogs having a 3-aryl-2-propenoyl moiety derived from alicyclic ketones were designed, synthesized, and investigated for cytotoxicity against murine B16 and L1210 cancer cell lines. The analogs belong to four structurally divergent series, three of which (series g, h, and i) contain differently substituted cyclopentanone units and the fourth (series j) contains a 3,3-dimethyl-4-piperidinone moiety. Of these, the analogs in series j showed potential cytotoxic activity against murine B16 (melanoma) and L1210 (lymphoma) cells. The most active compounds 5j, 11j, 15j, and 12h produced IC50 values from 4.4 to 15μm against both cell lines. A single-crystal X-ray structure analysis and molecular modeling studies confirmed that these chalcones have an E-geometry about the alkene bond and possess a slightly 'twisted' conformation similar to that of combretastatin A-4. At a concentration of 30μm, compounds 5j, 11j, and 15j did not cause microtubule depolymerization in cells, suggesting that they have a different mechanism of action. Forty-four novel chalcone-inspired analogs were designed and synthesized. Several compounds gave IC50 values 4.4-15μm against the growth of L1210 and B16 murine cancer cells.

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