1338320-08-3

Upstream product

• 1338225-76-5 (3R)-3-[(2S)-2-hydroxy-2-(4-chlorophenyl)ethyl]-2-[(1S,5R)-5,8,8-trimethyl-2-oxo-3-oxabicyclo[3.2.1]octane-1-carbonyl]-2,3-dihydroisoindol-1-one 
• 1338225-91-4 (3S,4aR)-3-(4-chlorophenyl)-3,4,4a,9-tetrahydro-1,3-oxazino[4,3-a]isoindole 
• 1338225-79-8 (3R)-3-[(2S)-2-hydroxy-2-(4-chlorphenyl)ethyl]-2,3-dihydro-1H-isoindol-1-one 
• 944052-55-5 (3R)-3-[2-(4-chlorophenyl)-2-oxoethyl]-2-[(1S,5R)-5,8,8-trimethyl-2-oxo-3-oxabicyclo[3.2.1]octane-1-carbonyl]-2,3-dihydroisoindol-1-one 

Relevant academic research and scientific papers

Synthesis of a series of γ-amino alcohols comprising an N-methyl isoindoline moiety and their evaluation as NMDA receptor antagonists

We report a series of new stereoisomeric γ-amino alcohols comprising an N-methyl isoindoline moiety as ligands for the ifenprodil binding site of the NMDA receptor. Among the four series of stereoisomers, 8a-c, 9a-c, 10a-c, and 11a-c, synthesised, the hig