1338332-57-2Relevant academic research and scientific papers
CHEMOENZYMATIC SYNTHESIS OF HEPARIN AND HEPARAN SULFATE ANALOGS
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Paragraph 0308; 0309, (2014/09/03)
The present invention provides a one-pot multi-enzyme method for preparing UDP-sugars from simple sugar starting materials. The invention also provides a one-pot multi-enzyme method for preparing oligosaccharides from simple sugar starting materials.
One-pot three-enzyme synthesis of UDP-GlcNAc derivatives
Chen, Yi,Thon, Vireak,Li, Yanhong,Yu, Hai,Ding, Li,Lau, Kam,Qu, Jingyao,Hie, Liana,Chen, Xi
, p. 10815 - 10817 (2011/11/04)
A Pasteurella multocida N-acetylglucosamine 1-phosphate uridylyltransferase (PmGlmU) was cloned and used efficiently with an N-acetylhexosamine 1-kinase (NahK-ATCC55813) and an inorganic pyrophosphatase (PmPpA) for one-pot three-enzyme synthesis of UDP-GlcNAc derivatives with or without further chemical diversification.
