1338360-75-0Relevant academic research and scientific papers
Synthesis of phenanthroindolizidine alkaloids and evaluation of their antitumor activities and toxicities
Ikeda, Takashi,Yaegashi, Takashi,Matsuzaki, Takeshi,Yamazaki, Ryuta,Hashimoto, Syusuke,Sawada, Seigo
, p. 5978 - 5981 (2011)
We previously reported that phenanthroindolizidine alkaloid 3 and its derivatives had markedly potent in vitro cytotoxicity. However, they had low in vivo antitumor activities and high in vivo toxicities, which was a serious problem. To address this probl
