133841-06-2

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Basic information

Product Name: 1H-INDAZOLE,3-BROMO-7-METHOXY-
Synonyms: 1H-INDAZOLE,3-BROMO-7-METHOXY-;3-BroMo-7-Methoxy-1H-indazole
CAS NO:133841-06-2
Molecular Formula: C8H7BrN2O
Molecular Weight: 227.06
EINECS: N/A
Product Categories: N/A
Mol File: 133841-06-2.mol
Article Data: 0

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: /
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: 1H-INDAZOLE,3-BROMO-7-METHOXY-(CAS DataBase Reference)
NIST Chemistry Reference: 1H-INDAZOLE,3-BROMO-7-METHOXY-(133841-06-2)
EPA Substance Registry System: 1H-INDAZOLE,3-BROMO-7-METHOXY-(133841-06-2)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 133841-06-2(Hazardous Substances Data)

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133841-06-2 Usage

Uses

3-Bromo-7-methoxy-1H-indazole is an intermediate in the synthesis of 7-Hydroxy Granisetron (H942675), a metabolite of Granisetron (G780000), a specific serotonin (5HT3) receptor antagonist. Used as an antiemetic. Granisetron HCl is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy. Its main effect is to reduce the activity of the vagus nerve. It does not have much effect on vomiting due to motion sickness. This drug does not have any effect on dopamine receptors or muscarinic receptor.

Check Digit Verification of cas no

The CAS Registry Mumber 133841-06-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,3,8,4 and 1 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 133841-06:
(8*1)+(7*3)+(6*3)+(5*8)+(4*4)+(3*1)+(2*0)+(1*6)=112
112 % 10 = 2
So 133841-06-2 is a valid CAS Registry Number.

133841-06-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name	3-bromo-7-methoxy-1H-indazole

1.2 Other means of identification

Product number	-
Other names	1H-INDAZOLE,3-BROMO-7-METHOXY-

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:133841-06-2 SDS

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