133843-77-3Relevant academic research and scientific papers
Synthesis of Casein-Related Peptides and Phosphopeptides. XII The Synthesis of O-Phosphoseryl-Containing Peptides with Site-Specific Serine Residues
Perich, John W.,Johns, R. B.
, p. 405 - 409 (2007/10/02)
The synthesis of the two Ser/Ser(P)-containing peptides H-Ser-Ser(P)-NHMeCF3CO2H and H-Ser(P)-Ser-Ser(P)-NHMeCF3CO2H is described.The selective use of Boc-Ser(PO3Ph2)-OH and Boc-Ser(Bzl)-OH in the Boc mode of peptide synthesis for the preparation of the protected Ser(Bzl)/Ser(PO3Ph2)-containing peptides is followed by platinum-mediated hydrogenolytic cleavage of the benzyl ether and phenyl phosphate groups.
