1338431-75-6Relevant academic research and scientific papers
Route selection and process development for a 5-piperazinylquinaldine derivative for the treatment of depression and anxiety
Cimarosti, Zadeo,Giubellina, Nicola,Stabile, Paolo,Laval, Gilles,Tinazzi, Francesco,Maton, William,Pachera, Roberta,Russo, Paola,Moretti, Ramona,Rossi, Sara,Cooke, Jason W. B.,Westerduin, Pieter
, p. 1287 - 1296 (2011)
1-(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl) -2-imidazolidinone, 1, was identified as a potential drug for the treatment of depression and anxiety. Herein is described the work carried out to select the manufacturing route and the proces
