1338468-23-7

Upstream product

• 53133-41-8 4-(benzylamino) but-3-en-2-one 
• 24424-99-5 di-tert-butyl dicarbonate 
• 51731-17-0 trans-4-methoxy-3-buten-2-one 
• 100-46-9 benzylamine 
• 187606-80-0 (E)-4-(benzylamino)but-3-en-2-one 

Downstream Products

• 1338468-31-7 C₂₁H₂₅NO₃ 
• 1338468-30-6 (1R,4R,9S,13S)-methyl 3-benzyl-13-hydroxy-3-azatricyclotridec[8.3.1.0(4,9)]-5-ene-1-carboxylate 
• 1338468-28-2 (1R,4R,9S)-methyl-3-benzyl-13-oxo-3-azatricyclotridec[8.3.1.0(4,9)]-5-ene-1-carboxylate 
• 1338468-29-3 (2S,6S,7R)-methyl 7-(benzyl(tert-butoxycarbonyl)amino)-1-oxospiro[5.5]undec-8-ene-2-carboxylate 
• 1338468-26-0 methyl 5-((1'S,2'R)-2-(benzyl(tert-butoxycarbonyl)amino)-1'-formylcyclohex-3'-enyl)pentanoate 
• 1338468-25-9 (1E,3E)-tert-butyl benzyl(6,6,6-trifluoro-5-oxohexa-1,3-dienyl)carbamate 
• 1338468-24-8 tert-butyl N-benzyl-N-[(E)-3-hydroxybut-1-enyl]carbamate 

Relevant academic research and scientific papers

A Method for the Preparation of β-Amino-α,β-unsaturated Carbonyl Compounds: Study of Solvent Effect and Mechanism

An efficient method for the preparation of β-amino-α,β-unsaturated carbonyl compounds is demonstrated. Bench-stable sodium 3-oxo-enolates were prepared from carbonyl compounds, and reacted with amines in the presence of an acid and a desiccant. DFT studie

PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN TREATMENT, AMELIORATION OR PREVENTION OF INFLUENZA

Provided herein is a compound of formula (I), optionally in the form of a pharmaceutically acceptable salt, solvate, polymorph, prodrug, codrug, cocrystal, tautomer, racemate, enantiomer,or diastereomer or mixture thereof, which is useful in treating, ameliorating or preventing influenza.

The enantioselective synthesis of tetracyclic methyllycaconitine analogues

A new enantioselective synthesis of ABEF ring analogues of methyllycaconitine has been developed using a chiral cobalt(III) salen-catalyzed Diels-Alder reaction to form the B ring. Subsequent elaboration to form the A, E and F rings was achieved by sequential Dieckmann, Mannich and Wacker-type cyclizations to afford tetracyclic analogues in 97.5% ee.