1338475-38-9

Upstream product

• 2728-04-3 N,N-diethyl-ortho-toluamide 
• 1338475-30-1 2-allyl-3-(4-methoxy-2-(methoxymethoxymethyl)phenyl)-2H-isoquinolin-1-one 
• 342816-20-0 2-hydroxymethyl-4-methoxybenzonitrile 
• 1338475-34-5 2-allyl-3-(2-hydroxymethyl-4-methoxyphenyl)-2H-isoquinolin-1-one 
• 1160616-34-1 3-(4-methoxy-2-(methoxymethoxymethyl)phenyl)-2H-isoquinolin-1-one 
• 1160616-66-9 4-methoxy-2-(methoxymethoxymethyl)benzonitrile 

Downstream Products

• 1338475-42-5 2-allyl-3-(4-methoxy-2-vinyl-phenyl)-2H-isoquinolin-1-one 

Relevant academic research and scientific papers

Synthesis of benzo[3,4]azepino[1,2-b]isoquinolin-9-ones from 3-arylisoquinolines via ring closing metathesis and evaluation of topoisomerase i inhibitory activity, cytotoxicity and docking study

Benzo[3,4]azepino[1,2-b]isoquinolinones were designed and developed as constraint forms of 3-arylisquinolines with an aim to inhibit topoisomerase I (topo I). Ring closing metathesis (RCM) of 3-arylisoquinolines with suitable diene moiety provided seven m