133857-62-2Relevant academic research and scientific papers
Tert-Butoxide-Mediated Arylation of 2-Substituted Cyanoacetates with Diaryliodonium Salts
Qian, Xiaofei,Han, Jianwei,Wang, Limin
, p. 940 - 946 (2016/04/05)
A transition metal-free direct arylation of 2-substituted cyanoacetates with diaryliodonium salts was developed. With this approach, a wide range of α-tolunitrile derivatives has been synthesized in good to excellent yields of 45-92%. Furthermore, the practicability of this approach is further manifested in the synthesis of a related bioactive agent of glutarimide.
The C-Arylation of α-Cyano Esters and Malononitriles by Aryllead(IV) Triacetates
Kozyrod, Robert P.,Morgan, Jacqueline,Pinhey, John T.
, p. 369 - 376 (2007/10/02)
The arylation of soft carbon nucleophiles by aryllead(IV) triacetates has been extended to α-cyano esters and malononitriles.Arylation did not occur with the parent compounds, ethyl cyanoacetate and malononitrile, but in both series monosubstituted compou
