1338582-40-3

Upstream product

• 1338582-43-6 (1-(2-chloroethyl)-3-(4-fluorophenyl)-1H-pyrazol-5-yl)methanol 
• 866588-11-6 3-(4-chlorophenyl)-1H-pyrazole-5-carboxylic acid ethyl ester 
• 403-42-9 1-(4-fluorophenyl)ethanone 
• 31686-94-9 ethyl 4-(4-fluorophenyl)-2,4-dioxobutanoate 
• 1338580-86-1 2-(4-fluorophenyl)-6,7-dihydro-4H-pyrazolo[5,1-c][1,4]oxazine 

Relevant academic research and scientific papers

COMPOUNDS AS CASEIN KINASE INHIBITORS

Provided are novel casein kinase inhibitors, or pharmaceutically acceptable salts thereof. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also provided.

METHODS FOR INHIBITING CASEIN KINASES

The present disclosure provides methods for inhibiting CK1 delta or CK1 epsilon activity, comprising administering an effective amount of the compound of Formula (I) to (IV), or a pharmaceutically acceptable salt thereof.

IMIDAZO-PYRIDAZNE DERIVATIVES AS CASEIN KINASE 1 DELTA/EPSILON INHIBITORS

The invention provides compounds of Formula (I) and pharmaceutically-acceptable salts thereof. The compounds of Formula (I) inhibit protein kinase activity thereby making them useful as anticancer agents.

Bicyclic Pyridinylpyrazoles

Bicyclic pyridinylpyrazoles of the formula (I) in which the symbols have the meanings given in the description and agrochemically active salts thereof and their use for controlling unwanted microorganisms in crop protection and the protection of materials