133868-73-2Relevant academic research and scientific papers
CHIRAL SILICON IN ASYMMETRIC SYNTHESIS. ADDITION OF ORGANOMETALLIC REAGENTS TO A SILYL THIONE CHIRAL AT SILICON
Bonini, Bianca F.,Maccagnani, Gaetano,Masiero, Stefano,Mazzanti, Germana,Zani, Paolo
, p. 2677 - 2680 (2007/10/02)
The reaction of R-(-)-methyl-α-naphtyl-phenylsilyl phenyl thioketone 1 with organolithium derivatives and Grignard reagents gives the α-silylsulphides 3 with medium to good levels of asymmetric induction.The asymmetry induced at the α-carbon is retained in the subsequent desilylation.
