133887-83-9

Basic information

• Product Name: 3,5-BIS-BOC-AMINOBENZOIC ACID
• Synonyms: 3,5-Bis((tert-butoxycarbonyl)aMino)benzoic acid;3,5-bis[(2-Methylpropan-2-yl)oxycarbonylaMino]benzoic Acid;3,5-BIS-BOC-AMINOBENZOIC ACID;BIS-BOC-3,5-DIAMINOBENZOIC ACID;BIS-TERT-BUTYLOXYCARBONYL-3,5-DIAMINOBENZOIC ACID;BOC2-3,5-DABA-OH;DI-BOC-3,5-DIAMINOBENZOIC ACID;BIS-T-BUTYLOXYCARBONYL-3,5-DIAMINOBENZOIC ACID
• CAS NO: 133887-83-9
• Molecular Formula: C₁₇H₂₄N₂O₆
• Molecular Weight: 352.38
• Product Categories: pharmacetical;Amino Acids
• Mol File: 133887-83-9.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 419.6°Cat760mmHg
• Flash Point: 207.6°C
• Appearance: /
• Density: 1.258g/cm³
• Vapor Pressure: 8.63E-08mmHg at 25°C
• Refractive Index: 1.578
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 3,5-BIS-BOC-AMINOBENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-BIS-BOC-AMINOBENZOIC ACID(133887-83-9)
• EPA Substance Registry System: 3,5-BIS-BOC-AMINOBENZOIC ACID(133887-83-9)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 133887-83-9(Hazardous Substances Data)

Usage

General Description

3,5-BIS-BOC-AMINOBENZOIC ACID is a chemical compound with the molecular formula C17H23NO6. It consists of two BOC-protected amino groups attached to a benzoic acid molecule at the 3 and 5 positions. BOC (tert-butyloxycarbonyl) is a commonly used protecting group in organic synthesis to prevent unwanted reactions. 3,5-BIS-BOC-AMINOBENZOIC ACID is often used in peptide synthesis as a building block for creating long chain peptides with specific sequences. It is also used in the pharmaceutical industry for the production of various drug compounds. 3,5-BIS-BOC-AMINOBENZOIC ACID is a white to off-white powder and is typically stored in a cool, dry place away from light and moisture.

InChI:InChI=1/C17H24N2O6/c1-16(2,3)24-14(22)18-11-7-10(13(20)21)8-12(9-11)19-15(23)25-17(4,5)6/h7-9H,1-6H3,(H,18,22)(H,19,23)(H,20,21)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 535-87-5 3.5-diaminobenzoic acid 

Downstream Products

• 918945-36-5 3-phenylpropyl 3,5-di-(tert-butyloxycarbonylamino)benzoate 
• 1404300-68-0 (3,5-bis(methylamino)phenyl)methanol 
• 136951-59-2 4-biphenyl 3,5-diaminobenzoate 
• 213680-79-6 (3-Azidocarbonyl-5-tert-butoxycarbonylamino-phenyl)-carbamic acid tert-butyl ester 
• 213212-88-5 3,5-diaminobenzoyl azide 
• 261724-01-0 benzyl 3,5-diaminobenzoate 
• 918945-32-1 3,5-Bis-[(S)-2-benzyloxycarbonylamino-3-(4-hydroxy-phenyl)-propionylamino]-benzoic acid benzyl ester 
• 918945-40-1 2-(naphthalen-1-yl)ethyl 3,5-diaminobenzoate 
• 918945-41-2 3,5-diamino-benzoic acid biphenyl-4-ylmethyl ester 

Relevant articles and documents

Liquid crystal alignment properties on polyamide films bearing a phenylenediacryloyl moiety in the main chain

Soluble photosensitive polyamide, which has a photoreactive 1,4-phenylenediacryloyl (PDA) moiety in the main chain with biphenyl side groups, was synthesized with high molecular weights. The polymer produced high quality films through conventional spin-ca

LINKER-DRUG AND ANTIBODY-DRUG CONJUGATE (ADC) EMPLOYING THE SAME

A linker-drug represented by formula (I) or a pharmaceutically acceptable salt or solvate thereof is provided. In formula (I), C is a conjugator, L is a linker unit, D is a toxin unit, and n is an integer ranging from 1 to 4. The structure of the conjugator is represented by formula (II). In formula (II), X is a leaving group, each of R1 and R2 is independently a single bond or —NH—, and Z is substituted aryl, heteroaryl, linear alkyl, cycloalkyl, heterocycloalkyl, or a combination thereof. The antibody is conjugated to the linker unit through a cysteine residue of the antibody. An antibody-drug conjugate (ADC) employing the above linker-drug is also provided.

ACETYLENE COMPOUND, SALT THEREOF, CONDENSATE THEREOF, AND COMPOSITION THEREOF

[Problem to be Solved] To provide an acetylene compound having a structure in which a unit having an amino group and a unit having an ethynyl group are bonded via a linking group, the acetylene compound being introducable to a polymer having thermal resis