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1-(DIPHENYLMETHYL)-3-METHYL-3-AZETIDINAMINE, commonly known as Diphenhydramine, is an antihistamine medication characterized by its chemical structure that includes a diphenylmethyl group and a methyl-3-azetidinamine group. It functions by inhibiting the effects of histamine, thereby mitigating the symptoms of allergic reactions and also serves as a sleep aid due to its sedative properties.

133891-52-8

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133891-52-8 Usage

Uses

Used in Pharmaceutical Industry:
1-(DIPHENYLMETHYL)-3-METHYL-3-AZETIDINAMINE is used as an antihistamine for treating symptoms of allergies and the common cold, such as itching, sneezing, and runny nose, by blocking the action of histamine in the body.
Used in Sleep Aid Applications:
1-(DIPHENYLMETHYL)-3-METHYL-3-AZETIDINAMINE is utilized as a sleep aid due to its sedative effects, helping to induce sleep and improve rest for individuals experiencing insomnia or other sleep disturbances.
However, it is important to note that due to its potential to cause drowsiness, 1-(DIPHENYLMETHYL)-3-METHYL-3-AZETIDINAMINE should be used with caution, particularly when engaging in activities that require alertness such as operating heavy machinery or driving.

Check Digit Verification of cas no

The CAS Registry Mumber 133891-52-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,3,8,9 and 1 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 133891-52:
(8*1)+(7*3)+(6*3)+(5*8)+(4*9)+(3*1)+(2*5)+(1*2)=138
138 % 10 = 8
So 133891-52-8 is a valid CAS Registry Number.

133891-52-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-benzhydryl-3-methylazetidin-3-amine

1.2 Other means of identification

Product number -
Other names 3-amino-1-diphenylmethyl-3-methylazetidine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:133891-52-8 SDS

133891-52-8Relevant academic research and scientific papers

ANTAGONISTS OF SNS SODIUM CHANNELS

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Page/Page column 35-36, (2010/11/25)

Compounds of the formula (I), and pharmaceutically acceptable salts thereof, are found to be antagonists of SNS sodium channels. They are therefore useful as analgesic and neuroprotective agents, formula (I): R1 represents: (a) -L-A or -L' -A'

7-Azetidinylquinolones as antibacterial agents. Synthesis and structure- activity relationships

Frigola,Pares,Corbera,Vano,Merce,Torrens,Mas,Valenti

, p. 801 - 810 (2007/10/02)

A series of novel antibacterial quinolones and naphthyridones has been prepared which contain 7-azetidinyl substituents in place of the usual piperazine or aminopyrrolidine groups. These azetidinyl derivatives were evaluated for in vitro activity by deter

Quantitative structure-activity relationships of antibacterial agents, 7-heterocyclic amine substituted 1-cyclopropyl-6,8-difluoro-4-oxoquinoline-3-carboxylic acids

Okada,Ezumi,Yamakawa,Sato,Tsuji,Tsushima,Motokawa,Komatsu

, p. 126 - 131 (2007/10/02)

Quantitative structure-activity relationships (QSAR) of various 7-(3-substituted-azetidin-1-yl)-1-cyclopropyl-6,8-difluoro-1,4-dihydro -4-oxoquinoline-3-carboxylic acids, 14-25, were studied to clarify the structural requirements for 3-substituted azetidi

Substituted 1-diphenylmethyl azetidines

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, (2008/06/13)

New azetidines, characterized in that they correspond to the general formula (I) STR1 in which R3 represents an amino radical, an alkylamino radical, a dialkylamino radical, a cycloalkylamino radical, an acylamino radical, an alkylacylamino radical, an aminomethyl radical, an alkylaminomethyl radical, an acylaminomethyl radical or an alkylacylaminomethyl radical, in which radicals each acyl fragment may be substituted with one or more halogen, especially fluorine, atoms; and R1, R2, R4, R5 and R6 represent a hydrogen atom or a lower alkyl radical, with the proviso that at least one of them represents a lower alkyl radical, and also their salts.

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