1338968-06-1

Basic information

• Product Name: C₂₅H₂₇NO
• CAS NO: 1338968-06-1
• Molecular Weight: 357.495
• Mol File: 1338968-06-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₅H₂₇NO(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₅H₂₇NO(1338968-06-1)
• EPA Substance Registry System: C₂₅H₂₇NO(1338968-06-1)

Safety Data

• Hazardous Substances Data: 1338968-06-1(Hazardous Substances Data)

Upstream product

• 259868-83-2 (S)-pyrrolidin-2-ylacetic acid methyl ester hydrochloride 
• 100-44-7 benzyl chloride 
• 113304-84-0 N-benzyl-(S)-proline methyl ester 
• 100-58-3 phenylmagnesium bromide 

Relevant articles and documents

A systematic study of chiral homoprolinols and their derivatives in the catalysis of enantioselective addition of diethylzinc to aldehydes

Homoprolinol analogs, a class of optically active γ-amino alcohols, were examined systematically in the enantioselective addition reactions of diethylzinc to aldehydes. By comparison of the results catalyzed by these γ-amino alcohols with those by the β-amino alcohols based on pyrrolidine architecture reported in the literature references, we have observed that the γ-amino alcohols are superior to the corresponding β-amino alcohols when the nitrogen and the oxygen are unsubstituted. Among the homoprolinols we tested, 2b gave the best results (45-88% yields, 44-81% ee) in the addition reactions. To the best of our knowledge, 2b has been noticed as one of the most efficient γ-amino alcohol catalysts based on pyrrolidine framework.