133910-35-7Relevant academic research and scientific papers
Highly Stereoselective Synthesis of Both Enantiomers of 2-Methyl-3-Hydroxythioesters by Asymmetric Aldol Reactions Using Similar Types of Chiral Sources Derived from L-Proline
Kobayashi, Shu,Horibe, Mineko
, p. 1029 - 1030 (2007/10/03)
Both enantiomers of 2-methyl-3-hydroxythioesters have been synthesized in chiral tin(II) Lewis acid-mediated aldol reactions of silyl enolate 3 with aldehydes, by simply choosing similar types of chiral sources, 4 and 5, derived from L-proline.
Asymmetric Aldol Reaction between Achiral Silyl Enol Ethers and Achiral Aldehydes by Use of a Chiral Promoter System
Kobayashi, Shu,Uchiro, Hiromi,Fujishita, Yuko,Shiina, Isamu,Mukaiyama, Teruaki
, p. 4247 - 4252 (2007/10/02)
In the presence of a chiral promoter consisting of tin(II) triflate, a chiral diamine, and tributyltin fluoride, the silyl enol ether of S-ethyl ethanethioate or S-tert-butyl ethanethioate reacts with aldehydes to afford the corresponding aldol-type adduc
