1339128-81-2Relevant academic research and scientific papers
Syn-Selective asymmetric cross-aldol reactions between aldehydes and glyoxylic acid derivatives catalyzed by an axially chiral amino sulfonamide
Kano, Taichi,Noishiki, Akira,Sakamoto, Ryu,Maruoka, Keiji
, p. 10626 - 10628 (2011)
syn-Selective asymmetric cross-aldol reactions of aldehydes with tert-butyl glyoxylate and glyoxamide were realized by the use of an axially chiral amino sulfonamide (S)-1. The cross-aldol products obtained are densely functionalized and readily converted to synthetically useful and important chiral building blocks such as γ-lactone and γ-lactam.
