133914-09-7

Basic information

• Product Name: Ethanone, 1-phenyl-2-(3-thiazolidinyl)-
• CAS NO: 133914-09-7
• Molecular Formula: C11H13NOS
• Molecular Weight: 207.296
• Mol File: 133914-09-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Ethanone, 1-phenyl-2-(3-thiazolidinyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-phenyl-2-(3-thiazolidinyl)-(133914-09-7)
• EPA Substance Registry System: Ethanone, 1-phenyl-2-(3-thiazolidinyl)-(133914-09-7)

Safety Data

• Hazardous Substances Data: 133914-09-7(Hazardous Substances Data)

Upstream product

• 504-78-9 1,3-thiazolidine 
• 70-11-1 α-bromoacetophenone 

Relevant articles and documents

Sequential ring expansion and ketene elimination reactions in the novel rhodium(I)-catalyzed carbonylation of thiazolidines

1,3-Thiazolidines react with carbon monoxide, in the presence of catalytic quantities of chloro(1,5-cyclooctadiene)rhodium(I) dimer and potassium iodide, to give thiazolidinones in 56-88% yields. Reaction in the absence of KI afforded the six-membered ring thiazin-3-one. The rhodium(I) complex can catalyze the quantitative conversion of the thiazin-3-one to the thiazolidinone under carbon monoxide, with ketene as the reaction by-product. The conversion of thiazolidines to thiazolidinones involves a novel regiospecific insertion of carbon monoxide into one of two ring carbon-nitrogen bonds, as well as a metal-catalyzed ketene elimination process.