133915-22-7

Basic information

• Product Name: 4-amino-2-(benzyloxymethyl)pteridine
• Synonyms: 4-amino-2-(benzyloxymethyl)pteridine
• CAS NO: 133915-22-7
• Molecular Weight: 267.29
• Mol File: 133915-22-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-amino-2-(benzyloxymethyl)pteridine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-amino-2-(benzyloxymethyl)pteridine(133915-22-7)
• EPA Substance Registry System: 4-amino-2-(benzyloxymethyl)pteridine(133915-22-7)

Safety Data

• Hazardous Substances Data: 133915-22-7(Hazardous Substances Data)

Upstream product

• 25911-65-3 2-amino-3-pyrazinonitrile 
• 133915-07-8 2-(benzyloxy)acetimidamide 
• 143-37-3 acetamidine 

Relevant articles and documents

Synthesis and potential antiallergic activity of new pteridinones and related compounds

The synthesis and pharmacological profile of a series of 2-alkoxy and 2-phenoxymethyl-3H-pteridin-4-ones and related compounds are described. These compounds displayed antiallergic activity in the passive cutaneous anaphylaxis test in rats. In contrast to both sodium cromoglycate and nedocromil sodium, many of our compounds were active when administered orally. The most potent in this series, 2-ethoxymethyl-3H-pteridin-4-one 2b (LCB 2183) was investigated in other models of allergy and inflammation. The antiallergic activity was confirmed and interesting antiinflammatory properties were observed. It was therefore selected for further development as a human therapeutic agent.