133933-25-2

Upstream product

• 133933-22-9 1-acetyl-4-hydroxy-2,6-dimethyl-1,2,3,4-tetrahydroquinoline 
• 133933-23-0 1-acetyl-4-oxo-2,6-dimethyl-1,2,3,4-tetrahydroquinoline 
• 42473-28-9 4-hydroxy-2,6-dimethyl-1,2,3,4-tetrahydroquinoline 
• 76858-72-5 diethyl N-(4-(prop-2-ynylamino)benzoyl)-L-glutamate 
• 133933-24-1 1-acetyl-6-(bromomethyl)-2-methyl-2,3-dihydroquinolin-4(1H)-one 

Downstream Products

• 133933-12-7 2-desamino-2-methyl-N¹⁰-propargyl-3,5,8-trideaza-1,2-dihydrofolic acid 

Relevant academic research and scientific papers

Folate analogues. 35. synthesis and biological evaluation of 1-deaza, 3-deaza, and bridge-elongated analogues of n10-propargyl-5, 8-dideazafolic acid1

Structural modifications at the pyrimidine ring and at the C9,N10-bridge region of the thymidylate synthase (TS) inhibitors N10-propargyl-5,8-dideazafolate (1; PDDF; CB 3717), 2-desamino-N10-propargyl-5,8-dideaz