133941-32-9Relevant academic research and scientific papers
Synthesis of Derivatives of FK 506 and FR 900520: Modifications at the Binding Domain
Emmer, Gerhard,Weber-Roth, Sabine
, p. 5861 - 5874 (2007/10/02)
The synthesis of 9-deoxo-FK 506 (13a), 9-deoxo-FR 900520 (13b), 9-deoxo-10(R)-deoxy-FR900520 (14) and its 10(S) isomer 15 is described.Radical deoxygenation/elimination of the 9-dihydro-9,10-thiocarbonates 5a,5b,6a and 6b gave the 9,10 unsaturated compoun
