133943-59-6 Usage
General Description
H-LEU-ARG-PRO-OH is a chemical compound that consists of three amino acids: leucine, arginine, and proline. H-LEU-ARG-PRO-OH is also known as leucyl-arginyl-proline and is often used in biochemical research. The "H" at the beginning of the name represents a hydrogen atom that is attached to the amino group of the first amino acid, leucine. The "OH" at the end of the name represents a hydroxyl group that is attached to the carboxyl group of the last amino acid, proline. This specific sequence of amino acids could possibly have certain biological activities or may be a part of larger peptide chains in specific proteins.
Check Digit Verification of cas no
The CAS Registry Mumber 133943-59-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,3,9,4 and 3 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 133943-59:
(8*1)+(7*3)+(6*3)+(5*9)+(4*4)+(3*3)+(2*5)+(1*9)=136
136 % 10 = 6
So 133943-59-6 is a valid CAS Registry Number.
133943-59-6Relevant articles and documents
Microencapsulation and modification of synthetic peptides of food proteins reduces the blood pressure of spontaneously hypertensive rats
Chen, Tzy-Li,Lo, Yung-Chieh,Hu, Wei-Tze,Wu, Ming-Chang,Chen, Shui-Ten,Chang, Hung-Min
, p. 1671 - 1675 (2003)
Synthetic peptides were microencapsulated into liposomes, cycled with a disulfide bond or modified with D-phenylglycine (D-phg) at the N-terminal, and their antihypertensive effects as orally administered (0.18 mM/kg body weight) to spontaneously hypertensive rats (SHR) were measured. The microencapsulated Leu-Lys-Pro reduced significantly the systolic blood pressures of SHR by 45 mmHg and showed a prolonged duration, revealing the significant protective effect of encapsulation. D-phg-Leu-Arg-Pro showed a duration about 2 h shorter than that of the peptide without modification. In addition, cyclic Leu-Arg-Pro peptide with a disulfide bond between the N- and C-terminal amino acids reduced the systolic blood pressure of SHR by 35 mmHg and displayed a lengthy duration.
