133950-71-7 Usage
Description
5-Bromo-3-indolyldecanoate is a chemical compound that serves as a chromogenic substrate in enzymatic assays, specifically for the detection of esterases and lipases. It is characterized by its ability to produce a blue-colored product upon hydrolysis by these enzymes, facilitating easy visual and spectrophotometric detection of their activity. 5-Bromo-3-indolyldecanoate is a valuable tool in research and diagnostic laboratories for studying enzyme kinetics, lipid metabolism, and the function of esterases and lipases in various biological processes. Furthermore, it plays a role in drug discovery and development by aiding in the screening of potential enzyme inhibitors and modulators.
Uses
Used in Research and Diagnostic Laboratories:
5-Bromo-3-indolyldecanoate is used as a substrate in enzymatic assays for the detection of esterases and lipases, allowing for easy visual and spectrophotometric identification of their activity. It is utilized to study enzyme kinetics and the role of these enzymes in biological processes.
Used in Drug Discovery and Development:
5-Bromo-3-indolyldecanoate is used as a screening tool for potential enzyme inhibitors and modulators, contributing to the advancement of pharmaceutical research and the development of new therapeutic agents.
Used in the Study of Lipid Metabolism:
5-Bromo-3-indolyldecanoate is employed as a substrate to investigate the function of esterases and lipases in lipid metabolism, providing insights into the regulation and mechanisms of these processes in biological systems.
Check Digit Verification of cas no
The CAS Registry Mumber 133950-71-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,3,9,5 and 0 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 133950-71:
(8*1)+(7*3)+(6*3)+(5*9)+(4*5)+(3*0)+(2*7)+(1*1)=127
127 % 10 = 7
So 133950-71-7 is a valid CAS Registry Number.
InChI:InChI=1/C18H24BrNO2/c1-2-3-4-5-6-7-8-9-18(21)22-17-13-20-16-11-10-14(19)12-15(16)17/h10-13,20H,2-9H2,1H3
133950-71-7Relevant articles and documents
Synthesis of indigogenic substrates. Investigation of Salmonella esterase activity
Agban,Ounanian,Luu-Duc,Monget
, p. 697 - 699 (2007/10/02)
The synthesis of chromogenic compounds of indoxyl as substrates is described. A first series is obtained from unsubstituted indoxyl esters and C7-C10 fatty acids. The 5 or 6-monosubstituted bromine or chlorine derivatives of indigogenic esters and 4,5 or 5, 6-disubstituted derivatives are synthezised in the second step. Some of them are evaluated on esterase activity in Salmonella cultures. The 5-bromo-indoxyl pelargonate derivative exhibits the most interesting results.
