13396-94-6

Usage

Uses

Used in Chemical Research:
1-(2,3-dihydro-1H-inden-5-yl)propan-2-amine is used as a research compound for exploring its chemical properties and potential applications in various chemical reactions.
Used in Pharmaceutical Industry:
1-(2,3-dihydro-1H-inden-5-yl)propan-2-amine is used as a building block in the synthesis of pharmaceuticals, where its reactivity and unique structure may contribute to the development of new drugs.
Used in Polymer Industry:
1-(2,3-dihydro-1H-inden-5-yl)propan-2-amine is used as a monomer or a component in the production of polymers, where its amine functionality can be utilized to form new polymeric materials with desired properties.
Used in Dye Industry:
1-(2,3-dihydro-1H-inden-5-yl)propan-2-amine is used as a precursor in the synthesis of dyes, where its chemical structure can be manipulated to create dyes with specific color characteristics and properties.

Upstream product

• 30084-91-4 indan-5-carbaldehyde 
• 496-11-7 INDANE 

Relevant academic research and scientific papers

Synthesis and Pharmacological Examination of Benzofuran, Indan, and Tetralin Analogues of 3,4-(Methylenedioxy)amphetamine

Benzofuran, indan and tetrahydronaphthalene analogs of 3,4-(methylenedioxy)amphetamine (MDA) were prepared in order to examine the role of the dioxole ring oxygen atoms of MDA in interacting with the serotonin and catecholamine uptake carriers.The series of compounds was evaluated for discriminative stimulus effects in rats trained to discriminate saline from the training drugs (S)-(+)-MBDB (1c), MMAI (3), and (S)-(+)-amphetamine and for the ability to inhibit the uptake of 3H>serotonin, 3H>dopamine, and 3H>norepinephrine into crude synaptosome preparations.Behaviorally, the benzofuran and indan analogs 4-6 produced similar discriminative cues, whereas the tetralin derivative 7 did not fully substitute for the training drugs.The results in the in vitro pharmacology studies indicate that selectivity for 5-HT versus catecholamine uptake carriers may be modulated by the position and orientation of ring oxygen atoms.However, the nonoxygenated isostere 6 possessed high potency at all uptake sites examined.Enlargement of the saturated ring by one methylene unit to give the tetralin derivative resulted in a large (3-4-fold) reduction in activity at catecholamine sites.