BIG ENDOTHELIN-1 (1-31) (HUMAN, BOVINE) is a synthetic peptide derived from the N-terminal 31 amino acids of human and bovine big endothelin-1. It is a potent vasoconstrictor that stimulates the release of norepinephrine in the vascular system and activates endothelin type A and type B receptors. This peptide exhibits biological activity in various tissues and organs and is widely used in research to study the physiological and pathological roles of endothelin-1 and its receptors.
Used in Pharmaceutical Industry:
BIG ENDOTHELIN-1 (1-31) (HUMAN, BOVINE) is used as a research tool for investigating the physiological and pathological roles of endothelin-1 and its receptors. It aids in understanding the mechanisms of action and potential therapeutic applications for cardiovascular diseases and other conditions involving endothelin signaling.
Used in Research Applications:
BIG ENDOTHELIN-1 (1-31) (HUMAN, BOVINE) is used as a research reagent to study the biological activity of endothelin-1 in various tissues and organs. It helps researchers explore the potential therapeutic applications of endothelin-1 in treating cardiovascular diseases and other conditions related to endothelin signaling.
Used in Drug Development:
BIG ENDOTHELIN-1 (1-31) (HUMAN, BOVINE) is used as a lead compound in the development of new drugs targeting endothelin signaling pathways. Its potent vasoconstrictor properties and ability to activate endothelin receptors make it a valuable candidate for the treatment of cardiovascular diseases and other conditions.
Used in Diagnostic Applications:
BIG ENDOTHELIN-1 (1-31) (HUMAN, BOVINE) is used as a diagnostic marker to assess the levels of endothelin-1 in biological samples. It helps in the early detection and monitoring of cardiovascular diseases and other conditions associated with endothelin signaling.
Used in Toxicology Studies:
BIG ENDOTHELIN-1 (1-31) (HUMAN, BOVINE) is used as a toxicological agent to evaluate the potential adverse effects of endothelin-1 and its analogs on various tissues and organs. It aids in understanding the safety profile of drugs targeting endothelin signaling pathways.

133972-52-8

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Basic information
1. Product Name: BIG ENDOTHELIN-1 (1-31) (HUMAN, BOVINE)
2. Synonyms: BIG ET-1 (1-31) (HUMAN, BOVINE);BIG ET-1 (1-31) (HUMAN, BOVINE) TRIFLUOROACETATE SALT;BIG ENDOTHELIN-1 (1-31) (HUMAN, BOVINE);BIG ENDOTHELIN-1 (1-31) (HUMAN, BOVINE) TRIFLUOROACETATE SALT;ENDOTHELIN-1 (1-31) (HUMAN);CYS-SER-CYS-SER-SER-LEU-MET-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-VAL-ASN-THR-PRO-GLU-HIS-VAL-VAL-PRO-TYR;H-CYS-SER-CYS-SER-SER-LEU-MET-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-VAL-ASN-THR-PRO-GLU-HIS-VAL-VAL-PRO-TYR-OH;Big Endothelin-1 (1-31) (huMan, bovine) Big ET-1 (1-31) (huMan, bovine)
3. CAS NO:133972-52-8
4. Molecular Formula: C162H236N38O47S5
5. Molecular Weight: 3628.15864
6. EINECS: N/A
7. Product Categories: N/A
8. Mol File: 133972-52-8.mol
Chemical Properties
1. Melting Point: N/A
2. Boiling Point: N/A
3. Flash Point: N/A
4. Appearance: /
5. Density: N/A
6. Refractive Index: N/A
7. Storage Temp.: -15°C
8. Solubility: N/A
9. CAS DataBase Reference: BIG ENDOTHELIN-1 (1-31) (HUMAN, BOVINE)(CAS DataBase Reference)
10. NIST Chemistry Reference: BIG ENDOTHELIN-1 (1-31) (HUMAN, BOVINE)(133972-52-8)
11. EPA Substance Registry System: BIG ENDOTHELIN-1 (1-31) (HUMAN, BOVINE)(133972-52-8)
Safety Data
1. Hazard Codes: N/A
2. Statements: N/A
3. Safety Statements: N/A
4. WGK Germany:
5. RTECS:
6. HazardClass: N/A
7. PackingGroup: N/A
8. Hazardous Substances Data: 133972-52-8(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 133972-52-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,3,9,7 and 2 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 133972-52:
(8*1)+(7*3)+(6*3)+(5*9)+(4*7)+(3*2)+(2*5)+(1*2)=138
138 % 10 = 8
So 133972-52-8 is a valid CAS Registry Number.

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