133978-59-3 Usage
General Description
2-(4-Amino-benzenesulfonylamino)-3-phenyl-propionic acid is a chemical compound with a molecular formula C15H15N3O4S and a molecular weight of 333.36 g/mol. It is a derivative of sulfonamide and has potential use as a non-steroidal anti-inflammatory drug (NSAID). 2-(4-AMINO-BENZENESULFONYLAMINO)-3-PHENYL-PROPIONIC ACID contains a sulfonamide group, which is known for its antibacterial and diuretic properties, and a phenyl group, which is commonly found in many NSAIDs. The presence of these functional groups suggests that this compound may have anti-inflammatory and analgesic properties, making it a potential candidate for pharmaceutical development. Further research is needed to fully understand its therapeutic potential and to establish its safety and efficacy for human use.
Check Digit Verification of cas no
The CAS Registry Mumber 133978-59-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,3,9,7 and 8 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 133978-59:
(8*1)+(7*3)+(6*3)+(5*9)+(4*7)+(3*8)+(2*5)+(1*9)=163
163 % 10 = 3
So 133978-59-3 is a valid CAS Registry Number.
InChI:InChI=1/C15H16N2O4S/c16-12-6-8-13(9-7-12)22(20,21)17-14(15(18)19)10-11-4-2-1-3-5-11/h1-9,14,17H,10,16H2,(H,18,19)/p-1/t14-/m1/s1
133978-59-3Relevant articles and documents
Design and synthesis of potent hydroxamate inhibitors with increased selectivity within the gelatinase family
Zapico, Jos Mara,Puckowska, Anna,Filipiak, Kamila,Coderch, Claire,De Pascual-Teresa, Beatriz,Ramos, Ana
, p. 142 - 156 (2015/02/05)
MMP-2 is a validated target for the development of anticancer agents. Herein we describe the synthesis of a new series of potent phenylalanine derived hydroxamates, with increased MMP-2/MMP-9 selectivity compared to analogous hydroxamates described previously. Docking and molecular dynamics experiments have been used to account for this selectivity, and to clarify the role of the triazole ring in the binding process. This journal is
