133981-22-3

Upstream product

• 133981-16-5 (1'S,5S)-1-Tosyl-3-(1'-phenyleth-1'-yl)-5-iodomethylimidazolidin-2-one 
• 133981-21-2 (1'S,5S)-1-Tosyl-3-(1'-phenyleth-1'-yl)-5-hydroxymethylimidazolidin-2-one 

Downstream Products

• 133981-23-4 (1'S,4S)-1-(1'-Phenyleth-1'-yl)-4-methoxycarbonylimidazolidin-2-one 

Relevant academic research and scientific papers

A new approach to the synthesis of enantiomerically pure 2,3-diaminoacids through chiral imidazolidin-2-ones

The synthesis of enantiomerically pure 5-iodomethylimidazolidin-2-ones (3a-c) and (4a-c) is reported, by means of iodocyclisation of allylic tosylureas (2a-c). Starting from pure (3a) and (4a), a synthesis of both (R)- and (S)-2,3-diaminopropanoic acid is