133983-63-8

Basic information

• Product Name: 4,5-Dimethyl-3-(ethoxycarbonyl)-1-phenyl-1,6-dihydrophosphinine
• Synonyms: 4,5-Dimethyl-3-(ethoxycarbonyl)-1-phenyl-1,6-dihydrophosphinine
• CAS NO: 133983-63-8
• Molecular Weight: 274.299
• Mol File: 133983-63-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4,5-Dimethyl-3-(ethoxycarbonyl)-1-phenyl-1,6-dihydrophosphinine(CAS DataBase Reference)
• NIST Chemistry Reference: 4,5-Dimethyl-3-(ethoxycarbonyl)-1-phenyl-1,6-dihydrophosphinine(133983-63-8)
• EPA Substance Registry System: 4,5-Dimethyl-3-(ethoxycarbonyl)-1-phenyl-1,6-dihydrophosphinine(133983-63-8)

Safety Data

• Hazardous Substances Data: 133983-63-8(Hazardous Substances Data)

Upstream product

• 623-73-4 diazoacetic acid ethyl ester 
• 30540-36-4 3,4-dimethyl-1-phenylphosphole 

Downstream Products

• 133983-64-9 4,5-Dimethyl-3-(ethoxycarbonyl)-1-phenyl-1,6-dihydrophosphinine 1-sulfide 

Relevant articles and documents

Reaction of Phosphole Sulfides with Diazoalkanes as a New Route to Phosphinines

The reaction of ethyl diazoacetate with 1-(methylthio)-3,4-dimethylphosphole 1-sulfide (6) in refluxing xylene leads to the corresponding diene-carbene cycloadduct 7.The stereochemistry of 7 was established by X-ray crystal structure analysis.Compound 7 is converted into 2-(ethoxycarbonyl)-4,5-dimethylphosphinine (4) upon reaction with triphenyl phosphite at 160 deg C.On the basis of the X-ray data, the proposed mechanism includes the opening of the cyclopropane ring of 7 with selective phosphorus-assisted migration of the ethoxycarbonyl group.This kind of chemistry can be transposed to a 2,2'-biphosphole to prepare a 2,2'-bisphosphinine.